Alignment, Assembly and Analysis Of Genomic Information

Mercator BioLogic has developed the next generation technology that will fundamentally transform genetic research. Our cutting-edge technology will set a new standard for the biological sciences, and open entirely new areas of discovery.

Currently, the industry standard for processing human genomes is measured in days. The fastest time of alignment and assembly we could find was by the Edico Dragen FPGA device which claims to have completed alignment of a 30X human genome in 22 minutes. The Dragen device is reported to cost over $300,000.00 and is generally difficult to configure and operate. The problem is that current methods take far too much time and result in very high cost to operate. Long compute times cause massive overruns in costs due to required human involvement and dedicated super computer cycles. We have reduced that time and the resulting costs we align and generate FULL gene panels much faster and at greatly reduced prices. Our most recent executions of full genome, 30X oversampled specimen takes 26 minutes. Exams take under 4 minutes, and transcriptomes are even faster.

We accomplished the above benchmark using a standard four-node Oracle RAC cluster, with 56 physical CPU processors and 256GB of RAM per node. The cost of this cluster is significantly less than the enterprise server computers that others typically use. Our tests from 20-core to 80-core servers have shown that there is no benefit to the expensive computer configurations. Our standard system is as fast at anything we could scale up to. What’s more, our software is much more accurate and reliable than current methods. Out of more than 1 billion string matches (including repetitive area matches) we had no acids that did not match in either sample. That represents an absolute zero error rate attributable to data anomalies.

Our proprietary system is capable of performing alignment, assembly, and analysis of any organism. The sequencing data input can be in any read length and from any device capable of producing FASTA, FASTQ, or any other formatted strings. We have performed benchmarks using 100bp, 50bp and 150bp FASTQ formatted scaffolds, and have tested the processes with other lengths of input strings up to 2,000bp, and with variable length inputs.

Mercator BioLogic partners with Chrono Engineering

February 17, 2017

Mercator BioLogic has completed a strategic partnership contract with Chrono Engineering of Salt Lake City, Utah. The capabilities of Chrono gives Mercator greater expertise in developing revolutionary new software, hardware and data storage technologies. The proven abilities of Chrono Engineering creates a much stronger team with far greater technical capabilities.

We are truly excited for the opportunity to join together with Chrono Engineering.

Partnership Negotiations with Thunder Biotech

August 5, 2017

Today Mercator BioLogic completed negotiations for a Letter of Intent from Thunder Biotech of Alpine, Utah. The team at Thunder have gained approval for a clinical trial of lung cancer therapy from the FDA and we are honored to be considered to participate with them in this exciting work.

In addition to the clinical trial, Mercator will forge a continuing partnership with a true innovator in this industry. We look forward to a long and exciting partnership.

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